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Pragmatic trials are studies designed to provide information for real-world clinical practice. They are often described as a focus on the practical aspects of study design, including the recruitment and consent process, as well as adherence and the use of routinely available equipment.

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Pragmatic Play, known for its slot machine games, also offers table-games like Bitcoin baccarat or Roulette. They have more than dozen licensed games and their software is known for its security and reliability. Their products are available across several languages and offer various betting options including live dealer tables.

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Pragmatic is a software company that provides a variety of casino games on online gambling platforms. Pragmatic's iGaming solutions are used by the most reputable operators as well as casinos with a physical location. The company offers front-end site design tools, analysis tools and marketing, promotions security payment systems, customer service and bug-reporting. In addition, the company provides its players a safe and secure environment with high-quality graphics and gaming.

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Another example of a trial that is pragmatic is the Home Blood Pressure Management (HBPM) study, which employed different investigators and participants from different geographic areas. This kind of heterogeneity is required for practical trials to be valid, and it also reduces the chance of bias in the results. Too much heterogeneity, however, can cause problems with the trial design.

Pragmatic Play is also a major player on the live casino market, offering an array of table games like as Blackjack and Roulette in various versions. The live studios of Pragmatic Play in Romania and Malta provide customers with an authentic gambling experience, as well a full variety of betting options via virtual. The company has also created various interactive games to make online gambling fun. Some of these shows have a live host, while others are hosted by prominent personalities from the industry.

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Pragmatic Play is a relatively new player in the online casino market, but it has made a name for itself through its mobile-friendly slot machines. Their games are optimized for mobile devices and run on HTML5 technology. They're also certified by reputable gaming authorities to ensure transparency and fairness. This is a good indication for players as it means that the games are checked and verified to ensure that the results of each round are random and unbiased.

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The majority of Pragmatic Play slot games feature traditional themes and modern graphics, making them popular with both newcomers and seasoned players. Many of them offer progressive jackpots and come with multiple bonus rounds and paylines. They aren't volatile, so you can enjoy a long gaming experience.

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Pragmatic Play is renowned for its top-notch games, and for offering an exceptional user experience. Its software is designed to work on mobile devices and is compatible with various languages. Despite its relatively young age, it has already established itself as a premier casino gaming platform. Wolves is one of its latest releases which is a five-reel slot machine that has a high RTP and impressive graphics. Other notable titles include Wolf Gold and Chilli Heat.

The purpose of pragmatic trials is to simulate real-life scenarios and gain maximum credibility externally. Usually, they are commissioned by policymakers and practitioners in order to inform their decisions. They can also be used to assess the causal relationship between an intervention and its effects. However, they should not, be used to replace the need for explanation studies.

The pragmatism idea is controversial and there are doubts about whether pragmatic trials can be used to replace explanation tests or if they are an alternative to them. Schwartz and Lellouch1 suggested the distinction between explanatory trials, which prove the clinical or physiological hypothesis as well as pragmatic trials, which inform policy and practice decisions. They also suggested an approach to pragmatic trials, dubbed PRECIS.2 This tool was designed to define the features of a pragmatic trial, including recruitment, design and delivery of the intervention, and follow-up.

The number of pragmatic trials is growing. A recent Medline search using the words pragmatic and naturalistic, which was restricted to randomised controlled trials (RCTs) returned 34 articles. They are displayed in red on Figure 2. This suggests that the health sciences community is becoming more aware of the importance of pragmatic thinking. It is important to remember that the majority of these studies were conducted in primary-care settings.