The two try to change back and discover that it was not the collision that causes the body swap but a kiss. The two try to reverse the change and discover kissing triggers the body swap. In the Natalie interview, Yoshikawa said that she had thought of the body swapping idea in the Yankee-kun days, and had researched some medical books on the differences between men and women, both physically and emotionally, but generally went with it because she liked the idea. She also said that the Yamada-kun characters go to a different school from the ones in Yankee-kun but that they live in adjacent neighborhoods. Manga author Miki Yoshikawa's previous work, Flunk Punk Rumble (Yankee-kun to Megane-chan) ran in Kodansha's Weekly Shōnen Magazine from 2006-2011, with a total of 211 chapters. It was serialized in Kodansha's shōnen manga magazine Weekly Shōnen Magazine from February 2012 to February 2017, with its chapters collected in 28 tankōbon volumes. On October 26, 2013, Crunchyroll announced a partnership with Kodansha where it would distribute chapters digitally to 170 countries using a new service called Crunchyroll Manga.

She is called Sae-chan by her students. Although the student council tries to shield each other from the powers while discovering and allying with the witches, they find themselves facing opposition from students controlled by the Shogi (japanese chess) club, which has male students with new kinds of witch powers. Supernatural stands as one of the few American-based live-action television programs of any kind to have ever been adapted into Japanese animation, as well as the first. At sexy Panties anime Expo 2015, she said that she initially thought about gender swapping first but later rejected that as a potential magic power. Ito takes Yamada to a closed-off room, but they learn from Odagiri who is with Ushio Igarashi that there is a captivation power that is the cause of this. Ryū Yamada has a hard time at school, with lousy grades and being bored. It stars Yusuke Yamamoto as the title character Ryū Yamada, and Mariya Nishiuchi as Urara Shiraishi. He confesses his love to Urara and they become a couple. Igarashi arrives and asks for Yamada's help to kiss Odagiri as she has fallen in love with Yamada. Ten years later, Yamada has become a successful businessman who is looked up to by his coworkers and keeps in touch with his high school friends, but has yet to propose to Urara.

He has been bored with his classes after one year of attending school.

Ryu Yamada is known as a delinquent in his high school. The prototype Yamada story eventually became the first chapter for Yamada-kun. He is responsible for deeming people worthy of meeting Kami; Goku is the first human he has ever deemed worthy. He also learns there areinues to manipulate the campaign, Yamada uses his copied seventh witch power to erase the recent events, but Ushio beats him to the punch and they are both forgotten by the students.