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Clinical trials that are designed to help inform practice in the real world are called pragmatic trials. They are typically focused on the practical aspects of study design, including recruitment and consent in adherence, 프라그마틱 무료 슬롯 (head to Jslt 28) as well as the use of routinely available equipment.

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A pragmatic study that involves a variety investigators and includes participants from various geographical regions is the Home Blood Pressure Management study (HBPM). This type of heterogeneity is necessary for pragmatic trials to be able to prove their validity and also reduces the chance of bias in the results. However too much heterogeneity could lead to issues with the design of the trial.

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The goal of pragmatic trials is to replicate real-life scenarios and gain the highest level of validity externally. Usually, they are requested by practitioners and policymakers to help guide their decisions. They can also be used to determine the causal relationship between an intervention and its results. They should, however, not be used to replace explanation studies.

The concept of pragmatism is controversial, and there are questions about whether pragmatic trials should replace explanatory tests or if they should serve as a complement to them. Schwartz and Lellouch1 suggested the distinction between explanatory trials, which confirm a physiological or clinical hypothesis, and pragmatic trials that inform policy and practice decisions. They also suggested a framework known as PRECIS for pragmatic trials.2 The tool was designed to define the characteristics of a pragmatic research study which includes recruitment, design, delivery of the intervention and 프라그마틱 무료슬롯 its follow-up.

There is a positive increase in the number of pragmatic trials that have been published. A recent Medline query that used the words naturalistic and pragmatic, restricted to randomised controlled trials (RCTs) returned 34 articles. They are displayed in red on Figure 2. This suggests that the health sciences community has become more aware of the importance of pragmatic thinking. It is important to note, however, that the majority of these studies were conducted in primary care settings.